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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T24020 |
DTS
Dibenzyl trisulfide |
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DTS is a selective and isoform-specific RSK1 kinase inhibitor. It also has broad cancer therapeutic potential. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01286 |
proHB-EGF Protein, Human, Recombinant (His)
heparin-binding EGF-like grow... |
Human | HEK293 Cells |
Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. Human HBEGF shows 76% and 73% aa sequence identity with rat and mouse HBEGF, respectively. It is required for normal cardiac valve formation and normal heart function, promotes smooth muscle cell proliferation. It may b... | |||
TMPY-02246 |
HB-EGF Protein, Human, Recombinant
DTSF,DTR,HEGFL,heparin-binding EGF |
Human | Baculovirus Insect Cells |
Heparin-binding EGF-like growth factor (HBEGF), a member of the EGF family of growth factors, exerts its biological activity through activation of the EGFR and other ErbB receptors. Soluble mature HBEGF is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen and chemotactic factor for fibroblasts, smooth muscle cells but not endothelial cells. HBEGF activates two EGF receptor subtypes, HER1 and HER4, and binds to cell surface HSPG. The transmembrane form of... |